News

Kiadis Pharma receives IND approval from FDA to start pivotal clinical trial with ATIR™ 08-07-2010
Biopharmaceutical Company Kiadis Pharma announced today that it has received approval for its Investigational New Drug (IND) application with the US Food and Drug Administration (FDA) to start the pivotal clinical study for its product ATIR™ in the United States. Kiadis Pharma is currently... read more 

Kiadis Pharma Provides ATIR™ Update: Two Year Follow-Up Data Show No Cases of Transplant Related Mortality - FDA grants ATIR™ Orphan Drug Status as a Medicinal Cell Based Therapy to Reduce Transplant Related Mortality 28-04-2010
Kiadis Pharma today provided an update on its cell therapy product ATIR™ developed for mismatched bone marrow transplants. ATIR™ continues to show excellent clinical results in patients who received a mismatched bone marrow transplantation from a family member donor. The two year follow up data... read more 

Theralux

The Theralux™ platform compromises a novel small molecule drug, TH9402 that has two specific properties:
- it is selectively retained in actively growing cells
- it can be activated by light to turn into a lethal compound

 

The light activation is accomplished by a proprietary medical device. The novel small molecule, the proprietary medical device and for each indication a specific treatment protocol together, form the basis of our photodynamic therapy (PDT) that allows the selective elimination of particular harmful cells.
 
The novel drug TH9402 is a non-toxic molecule that passively diffuses into all cells and collects in the mitochondria. In actively growing cells that have an inactive P-glycoprotein (Pgp) pump the drug is retained. Actively growing cells are for example cancer cells and activated immune cells.
 
TH9402 is inactive but once exposed to a specific wavelength of visible light it becomes activated and turns into a lethal compound for cells its retained in.


 

Image Theralux - ATIR™

Image Theralux - Reviroc™

Image Theralux - Rhitol™

Kiadis Pharma

Entrada 231-234
1096 EG  Amsterdam
The Netherlands


T +31 (0)20 314 02 50
F +31 (0)20 314 02 51